"Stand-alone Operation
The Digiface Dante can be used stand-alone, powered by the included power supply. Alternatively USB bus power from a USB power wall wart or USB battery can be used. When not connected to a computer host the device operates as 64 channel MADI to/from Dante converter. All channels are transferred to the other format unchanged, both ways.
To make most use of the additional Phones output, a submix of all MADI and Dante input channels can be set up in computer-connected operation, and stored in the Digiface Dante for stand-alone operation."

the manual tells in the first chapter "1. Introduction".

"Thank you for choosing the Digiface Dante. This unique, compact and portable audio interface is capable of transferring USB digital audio data and MADI from/to Mac or PC to the world's most popular audio network, Dante."

How should that work if you can't route between USB, MADI, and Dante?

Can the RME Digiface Dante convert from MADI to Dante? (MADI IN, Dante OUT)

Thanks
Alex