Little recommendation. If you want to enable (and motivate) people to support you, then it would be useful to deliver information which are needed to be able to help you ;-)
Information about your system and driver versions...
CPU, Mainboard, DRAM, GPU ...
What RME recording interface, firmware/driver version, how / to what port connected.
To which USB port / PCIe slot is your RME interface connected ?
IF USB: to a port coming from chipset or a 3rd party chip on the mainboard ?
Did you try all other USB ports or a different USB cable whether it makes a difference ?
If you have RME ASIO driver installed, do you see CRC errors in the driver settings ?
IF PCIe: which mainboard slot, did you try other ?
And in terms of "usb problems again".
What old problem when ?
What fixed the issue, how long did it run without problems ?
At what day exactly did the problems reoccurr ? Same or similar problem ? What has been changed on the system or environment that could be mapped to the re-occurrence of the issue ?
Maybe a Windows Update ?
Did you check Windows Update history, whether a particular Update has been installed?
Please note that Windows also deploys 3rd party drivers now if you customized it this way.
I remember that there was an option to activate updates also for Intel, nVidia, etc drivers.
Also helpful, an URL to the thread where your previous issues have been discussed.
Many thanks for further information.
Side comment: using latest drivers is no information. 1. you might be wrong, 2. nobody knows, what exact firmware and driver version is involved in this case to be able to correlate this with other issues.
X10SRi-F, E5-1650v4, Win10Pro20H2, Cub11Pro, UFX+ (v0.9735), XTC, 12Mic, ADI-2 Pro FS R BE