Maybe this: Option in TM FX, Store for Current or all users in Preferences

TotalMix FX stores all settings, workspaces and snapshots for the current user in:

XP: C:\Documents and Settings\ Username\Local Settings\ Application Data\TotalMixFX

Since Vista: C.\Users\Username\AppData\Local\TotalMixFX

Current User ensures that when workstations are used by several people they all find their own settings. In case the settings should be identical or given for any user, TotalMix FX can be changed to use the All User directory. An admin could even write protect the file lastFireface 8001.xml, which results in a complete reset to that file’s content whenever TotalMix FX is restarted. The xml-file is updated on exit, so simply set up TotalMix as desired and exit it (right mouse click on the symbol in the notification area or Exit), then change the file attribute.

Paths under macOS X

Mac Current User: user/Library/Application Support/RME TotalMix FX

Mac All Users: /Library/Application Support/RME TotalMix FX

Thanks for clarifying this. The Settings are not influenced from TotalMix. They are stored in a preferences file, and updated on shutdown. I will check that, but it needs some days.

I checked with macOS 10.15.6 and it works as expected. The current state is saved in

de.rme-audio.FirefaceSettings.plist

found in the hidden Library (Alt Go) under Preferences.

This file is loaded by the driver on boot automatically, its settings therefore always set on boot.

Settings 'Stored' via the Settings dialog are also stored in the unit, so if the current state is different then the unit will change its settings as soon as the Mac starts. Otherwise they should stay the same, and they did here.