No solution, I'm afraid, but I have a similar problem.
I recently moved my AES32 from an XP machine to my new PC - i7 Skylake, 32gB, running Windows 10. I've turned off processor throttling.
I've loaded the latest rme driver and updated the flash.
I don't use the daughter board, as I only want a max of 3 AES pairs.
My DAW is Sadie 6.1 which recognises the rme card perfectly.
I'm working in ASIO mode
AES pair 1 I use for monitoring via a Sound Devices 722
AES pair 4 feeds a Bricasti using AES4 return to the mixer.
RME settings are on internal and it's set to single wire and professional
44.1 projects run fine. The sample rate changes correctly and the Bricasti syncs at the correct sample rate and no glitching with 256 in the buffer.
For 96k projects, the sample rate changes correctly in settings, the Bricasti syncs, but the output sound is heavily distorted, with a sound like someone shaking a spring-line reverb (showing my age!)
When I first installed the card, I couldn't get it to work at 44.1 either, but by disabling windows sounds and the internal sound card and making sure the rme was not being used for WDM, it all came to life for 44,1 but not 96k
I'm sure I'm doing something stupid, so any ideas?
Thanks
Outhouse