As usual, using two Setups is the universal solution.

Loading certain “Setups” can be assigned to a button push.
Read manual page 26 (DAC) or 28 (Pro).

Watch out:
The  “Remap key” configuration is part of each individual “Setup” and needs to be set for each individual “Setup”.
This can be used to toggle through 2 or more Setups with one single button.

Works like this:
As the button assignment isn’t global, but part of each “Setup”, you can even have different assignments to the same button in each Setup - a nice feature that we can use for the following:

Choose ONE single button that you usually don’t need.

In Setup 1 assign: “load Setup 2”
In Setup 2 assign: “load Setup 1”
Now this single button toggles between both Setups.

This method can be extended to load even more Setups if needed, like:
In Setup 1 assign: “load Setup 2”
In Setup 2 assign: “load Setup 3”
In Setup 3 assign: “load Setup 4”
In Setup 4 assign: “load Setup 1”
Now the single button circles through Setup 1-4, clever, isn’t it?!

As for loading Setups ADI-2 asks for confirmation, a double-push is needed to execute the load.
Holding the button more than 1s, the button‘s original function is available.
Therefore I typically assign the SETUP button to load Setups – sic!