Hi Matthias, thanks for the response.  No, unfortunately nothing seems to cause this, and the Totalmix app itself hasn't completely hung - parts of it are still operational.  It simply won't let me adjust fader levels (or if they're not at unity they will snap to unity as soon as they're touch), create groups, etc.  It's like I'm locked out of making any changes.  Also, as I mentioned, it won't reflect any of my previously saved presets when recalled (I had some advanced routings which include loopback on several channels).

Very strange!

No, all is well with my keyboard ;-)  In fact, wondering if there was something different in the latest firmware, I actually TRIED holding all combinations of modifier keys to try and regain control of Totalmix, and none of them had any effect.  When I rebooted this morning as was well again - we'll see what happens.

Regardless though, I still am not having any luck with loading previously saved presets.  I wonder - is it possible to load the previous firmware & drivers, or would that be asking for trouble?  I never had any problems in the previous 7 years with my beloved FF800 ;-)

Well, I'm not doing anything out of the norm or using any special key macros or programs that "hold" a certain key.  I use Logic all day long which is heavily reliant on key commands, many of which also use modifier keys - all is well there.  Something is definitely out of whack with Totalmix as it's changing its behavior without any input from me - until I go to make a change and all of a sudden it won't let me!  I've also noticed that once it starts acting like this, it won't let me create groups anymore; it will only allow me to engage loopback.

As for presets, what happens is that I go to File > Open (or 'Open All Presets' - I have both types of files saved) but opening these files has no effect whatsoever.  Nothing gets recalled - no fader positions, labels, loopback status - nothing.  Also, when I booted up this morning I created a new preset from scratch then saved it.  Once it started acting up this afternoon, I tried recalling that preset - nothing.  No change.

I could take a screen capture video if you like and show you what it's doing - something's definitely not right.  Right now for example, I hit preset 1 which I've kept as a factory default.  The Phones submix has the faders at -6.0.  As soon as I try to move them, they snap to zero and then I can't move them at all.

Thanks Matthias for your responses - any other ideas?

I haven't found a consistent pattern yet.  It has helped once or twice, but other times it doesn't.  And I'm not of those "close the window" only guys - I'm a proper quitter ;-)  It does behave fine after a cold boot though; it just seems to start misbehaving after a while.

Thanks again for your replies - one of the many reasons I'm an RME fan.

Good morning... just cold-booted my rig (including FF800), and TM is acting strange right away.  At the moment it won't let me create groups.  I click the desired channels, they at least turn yellow, but moving one fader won't move the others.  This time, however, the loopback channels were at least activated and it remembered the channel labels.

Would there be any benefit to trashing preferences?  Or is there a way to hard reset the unit or re-flash the firmware?  Just curious...