The 2 analog inputs are analog inputs no micro preamps.
Whenever an application has the possibility to change the volume you can control it from the application.
If you are under Windows and
- use the ASIO driver with a DAW, then you can control the output in the DAW
- use an application which has no ASIO support, but uses the WDM driver, then you can control the volume inside the application as far as I remember
This interface has reference quality.
But its not a typical recording interface and doesn't come with Totalmix.
Read the manual, what it can do for you. Its clearly described there.
Very versatile unit, its killer in terms of quality + features + form factor for the price !
See also here for reviews of the device.
https://www.forum.rme-audio.de/viewtopic.php?id=24493
BR Ramses - UFX III, 12Mic, XTC, ADI-2 Pro FS R BE, RayDAT, X10SRi-F, E5-1680v4, Win10Pro22H2, Cub14