ADI-2 Pro can do this, but not all individually at the same time.

ADI-2 Pro has 2 fully independent DSP / DAC signal paths, 1/2 and 3/4.

1/2 can serve:
• Analog Line Out.
• Digital AES, Coax and Optical Out.
• Front PH 1/2 Headphones Out.

3/4 is serving Front PH 3/4 Headphones Out.

There are options to switch front/back just by plugging headphones, but:
Most comfortably, using “Setups”, you can activate the outputs you need for the very moment, leaving all plugged.

“Setups” can be recalled by a button push.
You can even cycle through a number of setups with a single button.

Exactly.
If this fits depends on how many destinations you want to feed at the same time.
For a single person this typically is just one.

ADI-2/4 Pro SE expands on this, as Rear TRSs can be assigned to Output 3/4.

• There’s an Auto-Standby function in ADI-2 with options from 30 min to 4 h inactivity / no audio signal.

• I’ve connected an ADI-2 Pro to an ADI-2/4 Pro SE and Auto Standby worked this way too, so there ‘s nothing on ADI-2’s side to stop it.

• In my studio I use groups of centralized mains power switching, so do save max. energy without caring about automatics.

The thing is almost all modern monitors all have DSP built in. Genelecs, neumann, dynaudio etc. Even if you input an analog signal, it will be converted to digital at some point.

I'm asking about the standby function because both my speaker setups are utilized quite often throughout each day. I don't like turning them off for only 8 hours or less each day so I rely on standby, which both have but currently I can only experience it via analog connection due to what I stated in my previous post.

I'd just like to know of the auto standby function of the 2 Pro or 2/4 affects the digital connection too or whether it's only available on analog connection.

My chain is foobar 2000 >>> ASIO MADIface USB >>> ADI-2 Pro FS >>> Coaxial Cable >>> Dynaudio Focus 600 XD: the speakers go to standby mode.

You need an audio interface supporting TotalMixFX for that:

• RME Babyface is the least expensive with “FX”.
• Digiface USB supports TotalMix without “FX”.

Both are limited to stereo I/O with ADI-2 Pro.

You can store and use a “Setup” for each configuration.
Read manual page 29 (DAC), 30 (Pro) or 29 (2/4 Pro SE).

Loading certain “Setups” can be assigned to a button push on the device or remote.
Read manual page 26 (DAC), 28 (Pro) or 30 (2/4 Pro SE).

Watch out:
The  “Remap key” configuration is part of each individual “Setup” and needs to be set for each individual “Setup”.
This can be used to toggle through 2 or more Setups with one single button.

Works like this:
As the button assignment isn’t global, but part of each “Setup”, you can even have different assignments to the same button in each Setup - a nice feature that we can use for the following:
Choose ONE single button that you usually don’t need.
In Setup 1 assign: “load Setup 2”
In Setup 2 assign: “load Setup 1”
Now this single button toggles between both Setups.

This method can be extended to load even more Setups if needed, like:
In Setup 1 assign: “load Setup 2”
In Setup 2 assign: “load Setup 3”
In Setup 3 assign: “load Setup 4”
In Setup 4 assign: “load Setup 1”
Now the single button circles through Setup 1-4, clever, isn’t it?!

As for loading Setups ADI-2 asks for confirmation, a double-push is needed to execute the load.
Holding the button more than 1s, the button‘s original function is available.
Therefore I typically assign the SETUP button to load Setups – sic!