Thanks ramses.

I tried routing to Adat 3/4 and 5/6 and enable playback there. Nobody hears me, nor do they hear reason. The only thing i can do is  selecting AN 1/2 so that they hear my voice. However i can't get the DAW audio to go through at the same time. The AN 1/2 in my totalmix does not have a Loopback button. What am i missing here?

As you can see there's no loopback button on AN 1/2.

Also how do you assign AN 1/2, or any other, to main out? I know main out is assigned to AN 1/2, but is that the same thing?

There is something you seem to get wrong, but I’m not sure what:
- you are talking about „AN 1/2“ in software playback row? There are no loopback buttons at all, they only are available in hardware output channels.
- you are talking about „AN 1/2“ assigned to Main out in control room section? As I already wrote, you have to click on the wrench symbol to open the tools then!

Main out and AN 1/2 is not the same. To have specific additional features or tools, there is the control room section. If you select „none“ for all the options main, speaker B, phones etc., all hardware outputs are appearing in order on the bottom row from left bottom corner on. For some applications, rather multimedia than studio usage, this can be more practical. Using TotalMix in mixing desk style, the control room section makes more sense.

Ups, didn't notice that he didn't select the settings behind the wrench symbol.

> [...] The only thing i can do is  selecting AN 1/2 so that they hear my voice. [...]

The information in post #3 sounded as if your application is limited to be able to get audio only from AN1/2.

But anyway, well done, you made it