Topic: Loud crack-pop and distorted audio (Windows 11)

I have a big problem here and can’t figure out who’s to blame.
I have RME Fireface 802 connected via FW (USB doesn’t work)
I changed a MB to be able to install Windows 11 and with new setup I experience regular loud crack-pop and distorted audio after that in Nuendo. This is related to recording/ monitoring only. Direct signal via totalmix is clear as well as audio playback in Nuendo.
Fix is switching any physical input or inserting external plugin in Nuendo

Audio glitch

i7-9700, 32GB RAM, NVidia GTX 1080 ti, RME Babyface Pro FS, Nuendo 11, Windows 10