Hi i63,

I can add to this: works superb!

To put an example. I connect the electric guitar to the Instrument input on my UFX III, sending this signal out to the amp.
The preamp return signal (from the amp’s effect send) feeds back into the UFX III.

From there, I:

• route it directly (also via TS cable) to the effect return of both combo amps (JCM900) with very (!) low latency to keep the dynamic of the preamp signal, and

• send it through external FX (Lexicon PCM 81) to add a 100% wet FX signal to the submix going toward the amps.

• send the guitar signal to a connected rack tuner (Korg Pitchblack X Pro)

This setup gives me flexibility for various use cases, such as:

• using the UFX III to create a parallel effects loop for my Marshall stereo setup,

• recording with to possibilites: via VSTi or the mic’d amp signal,

• reamping through VSTi or connected amps to use e.g. different Gain/EQ settings, and

• applying the external FX to the amp, DAW, or both. PCM81 (incl. modulation effects) for guitar and PCM91 (which is a pure reverb unit) for DAW).

All of this is supported by TotalMix FX and its excellent routing capabilities.

You can see my setup and routing of external FX in this Excel, see blog article with attached Excel, more info and URL here:
https://forum.rme-audio.de/viewtopic.php?id=40391

There I documented the current setup / state before doing further changes to the setup.
The routing of FX you find in the Excel, see the last tabs with
- TAB "Screenshots Matrix", e.g. Snapshot 3 "PCM81 -14" which means the FX 100% wet with -14 to the two amps submix
- TAB "Snap3", this TM FX documented in Excel format