I have a system which connect my DAW to my digital mixer via a digiface. The specs of my system are:

Mainboard :    MSI X58A-GD65 (MS-7522)
Chipset :    Intel X58
Processor :    Intel Core i7 0 @ 2800 MHz
Physical Memory :6144 MB (3 x 2048 DDR3-SDRAM )
Video Card :    ASUS EAH4350 series
Hard Disk :    HDT722520DLA380 (200 GB)
Hard Disk :    Hitachi (160 GB)
Hard Disk :    ST3500418AS (500 GB)
DVD-Rom Drive :    TSSTcorp CDDVDW SH-S223B ATA Device
Monitor Type :    ViewSonic VE710s - 17 inches
Network Card :     RTL8168/8111 PCIe Gigabit Ethernet Adapter
Operating System :    Windows 7 Professional Professional 6.01.7600  (x64)
DirectX :    Version 10.00

I work mainly on Ableton live 8.2.1 and Protools 9. Ableton live run as a charm, but ProTools 9 causes glitches and clicks even at large buffer size. Since everything is running fine i guess the problem is with protools. However, I installed asio4all driver (in despair coz i really want my 64bit DAW) it seems to work, but with some latency of its own. I really want to run protools using the digiface drivers. These are some other observation i made;
1. on clicking the Launch App Setup in protools HDSP the hdsp utility does not launch (However the Asio4all launches if selected)
2. If i change the buffer size in the hdsp utility, protools requires a restart, but when the same is done using asio4all configuration utility, the session closes and restart with new parameters
3. Totalmix works with asio4all
4. My digiface is flashed up to date and using the latest drivers