Nuendo 5.1.1
OSX 10.6.7 (freshly installed)
RME Fireface (x2) 2.91
UAD PCIe Quads (x3)
MacPro 1,1

I have this reoccurring issue and I'm not sure who is to blame so I posting on all related forums.

Every time I open the attached session and hit play no playback occurs. No channel meters show activity. When I try and adjust any sound card related setting like reset the hardware buffer, change routing in vst connections, Nuendo freezes. Upon force quit there is a report (attached).

I can repro this freeze over and over after multiple system restarts. My system has been fully reinstalled a week ago. New fresh OSX, Nuendo 5.1.1, RME drivers, UAD software.

here is the top of the report….

Date/Time:       2011-05-17 10:56:13 -0700
OS Version:      10.6.7 (Build 10J869)
Architecture:    x86_64
Report Version:  7

Command:         Nuendo
Path:            /Applications/Nuendo 5.app/Contents/MacOS/Nuendo 5
Version:         5.1.1.651 (5.1.1.651)
Parent:          launchd [140]

PID:             188
Event:           hang
Duration:        5.34s (sampling started after 2 seconds)
Steps:           13 (100ms sampling interval)

Pageins:         30
Pageouts:        0

Process:         Nuendo 5 [188]
Path:            /Applications/Nuendo 5.app/Contents/MacOS/Nuendo 5
UID:             501

  Thread 4d3        DispatchQueue 100
  User stack:
    13 ??? (in Nuendo 5 + 5270) [0x2496]
      13 ??? (in Nuendo 5 + 17947872) [0x111ece0]
        13 ??? (in Nuendo 5 + 6528175) [0x63acaf]
          13 CResampleBase::~CResampleBase() + 1060928 (in Nuendo 5) [0x1458740]
            13 CResampleBase::~CResampleBase() + 1382841 (in Nuendo 5) [0x14a70b9]
              13 CResampleBase::~CResampleBase() + 4023888 (in Nuendo 5) [0x172bd50]
                13 -[NSApplication run] + 821 (in AppKit) [0x913ed247]
                  13 -[NSApplication nextEventMatchingMask:untilDate:inMode:dequeue:] + 156 (in AppKit) [0x9142afce]
                    13 _DPSNextEvent + 847 (in AppKit) [0x9142b78d]
                      13 BlockUntilNextEventMatchingListInMode + 81 (in HIToolbox) [0x902aba3e]
                        13 ReceiveNextEventCommon + 354 (in HIToolbox) [0x902abbb9]
                          13 RunCurrentEventLoopInMode + 392 (in HIToolbox) [0x902abe04]
                            13 CFRunLoopRunInMode + 97 (in CoreFoundation) [0x9990f291]
                              13 CFRunLoopRunSpecific + 452 (in CoreFoundation) [0x9990f464]
                                13 __CFRunLoopRun + 8059 (in CoreFoundation) [0x99911adb]
                                  13 CResampleBase::~CResampleBase() + 4023686 (in Nuendo 5) [0x172bc86]
                                    13 CResampleBase::~CResampleBase() + 1394875 (in Nuendo 5) [0x14a9fbb]
                                      13 CResampleBase::~CResampleBase() + 1394262 (in Nuendo 5) [0x14a9d56]
                                        13 CResampleBase::~CResampleBase() + 255663 (in Nuendo 5) [0x1393daf]
                                          13 ??? (in Nuendo 5 + 14755818) [0xe137ea]
                                            13 ??? (in Nuendo 5 + 12121036) [0xb903cc]
                                              13 ??? (in Nuendo 5 + 15491655) [0xec7247]
                                                13 CResampleBase::~CResampleBase() + 4461559 (in Nuendo 5) [0x1796af7]
                                                  13 semaphore_wait_trap + 10 (in libSystem.B.dylib) [0x92cd70d6]
  Kernel stack:
    13 semaphore_wait_continue + 0 [0x22a3e1]

  Thread 66c        DispatchQueue 126483205
  User stack:
    13 thread_start + 34 (in libSystem.B.dylib) [0x92d04682]
      13 _pthread_start + 345 (in libSystem.B.dylib) [0x92d047fd]
        13 VFoundation::VJobServer::ServerThreadProxy(void*) + 21 (in BFD2) [0x3db734c3]
          13 VFoundation::VJobServer::ServerThread() + 348 (in BFD2) [0x3db72d90]
            13 VFoundation::VSemaphore::WaitForSemaphore(long) + 82 (in BFD2) [0x3db86ce2]
              13 usleep$UNIX2003 + 61 (in libSystem.B.dylib) [0x92d30e03]
                13 __semwait_signal + 10 (in libSystem.B.dylib) [0x92d05046]
  Kernel stack:
    13 semaphore_wait_continue + 0 [0x22a3e1]

  Thread 69b        DispatchQueue 910410781
  User stack:
    13 thread_start + 34 (in libSystem.B.dylib) [0x92d04682]
      13 _pthread_start + 345 (in libSystem.B.dylib) [0x92d047fd]
        13 VSTPluginMain + 441163 (in POD Farm Guitar Amps) [0x805b6e65]
          13 VSTPluginMain + 335520 (in POD Farm Guitar Amps) [0x8059d1ba]
            13 ??? (in POD Farm Guitar Amps + 638188) [0x805e3cec]
              13 VSTPluginMain + 194962 (in POD Farm Guitar Amps) [0x8057acac]
                13 pthread_cond_wait + 48 (in libSystem.B.dylib) [0x92d4d45f]
                  13 semaphore_wait_signal_trap + 10 (in libSystem.B.dylib) [0x92cd70e2]
  Kernel stack:
    13 semaphore_wait_continue + 0 [0x22a3e1]

  Thread 690        DispatchQueue 934010806
  User stack:
    13 thread_start + 34 (in libSystem.B.dylib) [0x92d04682]
      13 _pthread_start + 345 (in libSystem.B.dylib) [0x92d047fd]
        13 TWXCommandInterface + 1684546 (in L6TWXY) [0x74757962]
          13 TWXCommandInterface + 1685185 (in L6TWXY) [0x74757be1]
            13 usleep + 61 (in libSystem.B.dylib) [0x92d5e6aa]
              13 mach_wait_until + 10 (in libSystem.B.dylib) [0x92cd71ae]
  Kernel stack:
    13 mach_wait_until_trap + 81 [0x2196fb]

  Thread 4d7        DispatchQueue 1634545000
  User stack:
    13 start_wqthread + 30 (in libSystem.B.dylib) [0x92cfcb66]
      13 _pthread_wqthread + 390 (in libSystem.B.dylib) [0x92cfcd21]
        13 _dispatch_worker_thread2 + 240 (in libSystem.B.dylib) [0x92cfd29e]
          13 _dispatch_queue_invoke + 163 (in libSystem.B.dylib) [0x92cfd4f9]
            13 kevent + 10 (in libSystem.B.dylib) [0x92cfd922]
  Kernel stack:
    13 kevent + 97 [0x4783e9]

  Thread 4dc       
  User stack:
    13 _pthread_body + 27 (in libSystem.B.dylib) [0x92dccd5e]
      13 ??? (in Nuendo 5 + 6992254) [0x6ac17e]
        13 semaphore_timedwait_trap + 10 (in libSystem.B.dylib) [0x92cd70ee]
  Kernel stack:
    13 semaphore_wait_continue + 0 [0x22a3e1]

  Thread 540       
  User stack:
    13 thread_start + 34 (in libSystem.B.dylib) [0x92d04682]
      13 _pthread_start + 345 (in libSystem.B.dylib) [0x92d047fd]
        13 AVS::DestroyAVCDeviceController(AVS::AVCDeviceController*) + 317 (in DVCPROHDMuxer) [0x1d4be98f]
          13 CFRunLoopRun + 84 (in CoreFoundation) [0x999153a4]
            13 CFRunLoopRunSpecific + 452 (in CoreFoundation) [0x9990f464]
              13 __CFRunLoopRun + 2079 (in CoreFoundation) [0x9991037f]
                13 mach_msg_trap + 10 (in libSystem.B.dylib) [0x92cd709a]
  Kernel stack:
    13 ipc_mqueue_receive_continue + 0 [0x210cea]

  Thread 541       
  User stack:
    13 thread_start + 34 (in libSystem.B.dylib) [0x92d04682]
      13 _pthread_start + 345 (in libSystem.B.dylib) [0x92d047fd]
        13 CAPThread::Entry(CAPThread*) + 140 (in CoreAudio) [0x941694a4]
          13 HALRunLoop::OwnThread(void*) + 162 (in CoreAudio) [0x9417d96e]
            13 CFRunLoopRunInMode + 97 (in CoreFoundation) [0x9990f291]
              13 CFRunLoopRunSpecific + 452 (in CoreFoundation) [0x9990f464]
                13 __CFRunLoopRun + 6523 (in CoreFoundation) [0x999114db]
                  13 __CFMachPortPerform + 338 (in CoreFoundation) [0x99915772]
                    13 IOA_HWDevice::MachPortCallBack(__CFMachPort*, void*, long, void*) + 693 (in CoreAudio) [0x9416c6bb]
                      13 IOA_MultiDevice::HWDevice_Paused(IOA_HWDevice*) + 168 (in CoreAudio) [0x9419296e]
                        13 CAMutex::Lock() + 63 (in CoreAudio) [0x9414a323]
                          13 semaphore_wait_signal_trap + 10 (in libSystem.B.dylib) [0x92cd70e2]