To add to Jesav's comment about "remarkably efficient" when it comes to driver updates. So true -- I bought my FF800 (which I absolutely LOVE, by the way) this past December and I've seen FOUR (count-them: 1-2-3-4) driver updates for this device since I've had it. All updates were quick, solid, and (the part I love) frequent. No doubt RME are actively working with Apple and testing/compiling Alpha drivers to test AS WE SPEAK. Most companies, when they are nose-down writing code, don't discuss it (for example Avid made a statement about PT Lion compatibility, but haven't said a thing about PT 9.0.5 Beta yet, likely already in testing) --- so you have to go on track-record: and RME's track-record is just awesome in this regard.
No doubt, somewhere in the coming weeks we'll get a driver. And over the coming weeks/months, one-by-one, every DAW will support 10.7.x, while also maintaining compatibility with at least 10.6.8. It's a foregone conclusion, and the early-adopter "professionals" just need to be patient. Since System 7, Mac OS9, etc...no matter how structured an OS beta program was hardware manufacturers were RARELY ready DAY ONE
RME and Apogee and everybody else want to know their product will work on those shiny new Macs -- and they will soon, no worries. And, unlike Apogee, RME has more Operating Systems to support in at least 4 different OS variants (10.6.x, 10.7.x, WinXP, and 7 -- I'm leaving out Vista & OSX 10.5.x here)
You know...you folks buying new Macs certainly should have an disk clone backup or DVD media of SL sitting around. All Mac users can still play with Lion as another boot partition while also keeping your 10.6.x OS available for production work (Super Duper or Carbon Copy Cloner, anyone??). There's just isn't much weight to this lost revenue argument, when there's all kinds of backups and nets a good professional can employ to both see Lion AND keep on working in 10.6.x while the industry adjusts to Lion.
Mac OSX 10.6.7 i7 8GB / PT & Logic 9 / RME FF800