Sorry if that question is dumb from a non-Windows user, no ASIO/WDM knowledge here, but: Does your remote software on the Windows rig maybe support none other audio input than inputs 1/2 of the local audio interface(s)? If so, a dedicated virtual routing software could be part of the remedy. In our (Mac-only) setup we run into this constraint with almost all chat / meeting (Teams, Google Meet, Zoom…) and far-end recording apps (Sessionlink, Studiolink) which we want to feed dedicated software returns and mixes from TotalMix to. Our solution is called Loopback, a Mac-only software by Rogue Amoeba which acts like a virtual patchbay between any ins and outs of your audio interface and the individual audio in/out of any app on your machine.

It typically works like this: For any app that only listens to inputs 1/2, you create a dedicated virtual „audio interface“ which looks like a physical soundcard to the app, but in the background is fed exactly the channels you want it to have. You choose that „interface“ as the audio input device or „mic“ within said app, and you’re set. I‘ve read about Windows solutions called „Virtual Cable“ or „Virtual Audio Cable“ which do the same, maybe VoiceMeeter falls into the same category.

You have to handle another layer of complexity, but have to set it only once, and you gain more routing flexibility than with the built-in loopback feature in TotalMix itself. I don’t know exactly what such virtual routing does to latency, probably quite a bit, but in a remote use scenario maybe that isn’t your biggest concern.