Yes.
For coupling of both output’s controls, switch ADI-2 Pro to to Balanced Phones Mode (manual page 44) if the speakers are a stereo pair.
Depending on the speakers/amps you can use balanced or single ended interconnects.
Just need the fitting cables.
Either way, you have to use 6.3 mm TRS jacks at ADI-2 Pro’s side, NEVER 6.3 mm TS!
Practically, the result should be not much different if you just use PH 3/4 OR PH 1/2 in normal stereo, with a splitter cable 6.3 mm TRS to you speaker connections.
What exactly are you heading for?