I use a UFX with total mix running on a laptop for live gigs and it works very well. In my case I also have iPads and iPhones wirelessly set up and using Touch OSC for each member to adjust his own mix. This can get complicated, but more due to the musicians than the hardware.

We have two guitars, bass, drums and vocals. We use 12 inputs (4 UFX pres plus 8 over ADAT) and five mixes including FOH.

But my set up not very relevant. Much depends on how many input channels and mixes you need and if you plan to use IEMs.

The only mixer is Total Mix. It is very powerful and flexible, and the effects are good.  Total Mix will likely meet your needs, but not sure the Babyface has enough ins and outs for you.  Again much depends on your own needs, but keep in mind that with IEMs you will want to mic everything. Even in small clubs where you might not need drum mics for FOH, you will want them for the IEMs.  Ideally you would have an audience mic too for the IEMs (can sound too isolated from the audience otherwise), but this is less critical.

I use the 4 UFX pres and an 8 channel external pre/converter unit (Onyx 800r) sent to the UFX over ADAT.  It has two headphone outs we use for hardwired IEMs (drums and bass as we don't move much), and run the outputs on the back to two wireless IEM units and to FOH (powered mains).

If you want/need to integrate with a house mixer this is a whole other layer of complexity, especially if you move from club to club.  Many club sound guys won't want to deal with adding a new and unknown system to their own.  We only use our UFX-based rig when we bring our own system entirely.  These issues go beyond RME hardware and TM.  You may want to check out Gearslutz for threads about pros and cons of IEMs.

You can just put an overhead mic on the drums. Move it to get optimum coverage. Use your ears.