Hello, I have the same issue here:
Windows 7 Pro 64bit
RME HDSPe RayDat
I tried everything (disabled antivirus, run the installer as administrator, unistalled previous driver).
Here is my log:
INFO: 03/03/2019 17:27:29
INFO: Product Version 2.1.0.0.
INFO: Version: 6.0.6000
INFO: Platform ID: 2 (NT)
INFO: Service Pack: 0.0
INFO: Suite: 0x0100, Product Type: 1
INFO: Architecture: AMD64.
INFO: Interactive Windows Station
INFO: Command Line: 'C:\Users\Master\AppData\Local\Temp\rme\dpinst64.exe'
INFO: DPInst is not multi-lingual.
INFO: ****************************************
INFO: Current working directory: 'C:\Users\Master\AppData\Local\Temp\rme'
INFO: Running on path 'C:\Users\Master\AppData\Local\Temp\rme'
INFO: User UI Language is 0x409.
INFO: Install option set: Force install if driver is not better.
INFO: Install option set: uninstall will be set to delete driver binaries.
INFO: Found driver package: 'C:\Users\Master\AppData\Local\Temp\rme\hdsp.inf'.
INFO: Preinstalling 'c:\users\master\appdata\local\temp\rme\hdsp.inf' ...
INFO: ENTER: DriverPackagePreinstallW
SUCCESS:c:\users\master\appdata\local\temp\rme\hdsp.inf is preinstalled.
INFO: RETURN: DriverPackagePreinstallW (0x0)
INFO: ENTER: DriverPackageGetPathW
INFO: RETURN: DriverPackageGetPathW (0x0)
INFO: ENTER: DriverPackageInstallW
INFO: Installing INF file 'c:\users\master\appdata\local\temp\rme\hdsp.inf' (Plug and Play).
INFO: Looking for Model Section [Devices.NTAMD64]...
INFO: Installing devices with Id "PCI\VEN_10EE&DEV_3FC6&SUBSYS_00000000&REV_D3" using INF "C:\Windows\System32\DriverStore\FileRepository\hdsp.inf_amd64_neutral_835d486b2d63ad8a\hdsp.inf".
INFO: ENTER UpdateDriverForPlugAndPlayDevices...
ERROR: RETURN UpdateDriverForPlugAndPlayDevices. (Error code 0x5: Access is denied.)
ERROR: Installation failed. (Error code 0x5: Access is denied.)
ERROR: PnP Install failed. (Error code 0x5: Access is denied.)
INFO: Attempting to rollback ...
ERROR: Rollback failed. (Error code 0x643: Fatal error during installation.)
INFO: RETURN: DriverPackageInstallW (0x5)
INFO: ENTER: DriverPackageUninstallW
INFO: Uninstalling driver package c:\users\master\appdata\local\temp\rme\hdsp.inf...
INFO: Successfully uninstalled 'C:\Windows\INF\oem11.inf'.
INFO: No devices found for C:\Windows\System32\DriverStore\FileRepository\hdsp.inf_amd64_neutral_835d486b2d63ad8a\hdsp.inf uninstall.
INFO: Successfully deleted properties for driver store entry 'C:\Windows\System32\DriverStore\FileRepository\hdsp.inf_amd64_neutral_835d486b2d63ad8a\hdsp.inf'.
SUCCESS:Uninstall completed.
INFO: RETURN: DriverPackageUninstallW (0x0)
INFO: Returning with code 0x80010000
INFO: 03/03/2019 17:28:18