Hello!
For 1st option,
if you re going to be using your Genelecs' digital connections, there's no point for the ADI 2 Pro, since the converters used for DA are going to be the Genelecs' ones. So you can connect them directly on the DF Usb.
2nd:
This is a viable setup and a great Mic Pre! If you 're going to be using your Genelecs, it's the one you need, since you don't need your UFX's Mic Pres. Maximum number of channels will be 24 In/ 34 Out @44.1/48K.
3rd:
This is the most futureproof setup, if you later decide to add more channels via MADI and the other connections it offers! Even another pair of monitors for taking use of the UFX+ 's converters.
Of course you can use an extra pair of analog monitors with the ADI 2 Pro of your 1st option, and benefit from the ADI 2 Pro's features such as SRC(SampleRateConversion), among others!
It depends on what your needs are!
So, to sum things up:
1. Medium futureproofing, option for extra pair of analog monitors, ADI 2 Pro FS R BE features
2. Medium futureproofing, great colouring Mic Pre
3. Major futureproofing, option for extra pair of analog monitors, great clean Mic Pres, DUREC and features of the UFX+
Hope this helps, a bit!
RME Gear: Digiface USB, HDSP 9632