Years ago, when the ADI-2 DAC FS was the 1st unit released with FS clock, there was a discussion in this forum, whether FS clock would lead to audible better sound. The final agreement was, that SNR and jitter suppression is measurable better, but not audible.
Getting a PCIe card with TotalMix FX could give you some flexibility in terms of routing, but is not really required if you do not need it.
But if you get such a card, for whatever reason, then I would use a TOSLINK connection, as vinark wrote.
Simple and straightforward. You can plug them directly between the devices, you can perform clock synchronization over any digital connection. There is no better or worse quality, it's simply a digital connection which also provides galvanic isolation like (as good as every) AES implementation does.
Otherwise, use USB. Keep it simple!
Hint: if somebody - maybe from another forum — would tell you that an "audiophile USB cable" is needed .. this is pure nonsense, save the money. This is also digital transmission of audio data over USB. I can recommend you Lindy cables, which have an excellent price / quality ratio. Up to 5 m is possible using USB2. Do not spend more than €15-25.
BR Ramses - UFX III, 12Mic, XTC, ADI-2 Pro FS R BE, RayDAT, X10SRi-F, E5-1680v4, Win10Pro22H2, Cub14