In Cubase 5 "VST Connections" window (under MacOS X5.8) the bus output assignments jump to channels which were not selected by any action on my part. After I select (control click on a bus), for example, bus Stereo out left to HDSPe MADI (PCI slot3) channel 23 and close the selection window, Stereo out left will reassign to channel 17 or channel 7 etc., after I close the selection window. In order to eliminate clumsy mouse technique as variable, I wrote and selected assignments via a bus assignment "preset" and the same thing happened.
The channel assigments do change in a predictable way when I go between 48kHz and 96kHz, but these unpredictable changes happen without a change in the sample rate at all four sample rates available on the Aplha.
Thanks, I hope this is clear enough.